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From the international Amalgam Mailing list :
Scientific Facts on the Biological Effects of Mercury Amalgams

oMercury penetrates the blood-brain barrier around the brain, and as
little as one part per million can impair this barrier, permitting entry
of substances in the blood that would otherwise be excluded.

--Chang and Hartman, 1972; Chang and Burkholder, 1974

oThe effect of mercury on the nervous system selectively inhibits
protein and amino acid absorption into brain tissue.

--Yoshino et al.,1966; Steinwall, 1969; Steinwall and Snyder, 1969;
Cavanagh and Chen, 1971

oMercury inhibits the synaptic uptake of neurotransmitters in the brain
and can produce subsequent development of Parkinson's disease.

--Ohlson and Hogstedt, "Parkinsons Disease and Occupational Exposure to
Organic Solvents, Agricultural Chemicals and Mercury" Scandinavian
Journal of Work Environment Health Vol 7 No.4 : 252-256,1981

oMercury is nephrotoxic (toxic to the kidneys) and causes pathological

--Nicholson et al, "Cadmium and Mercury Nephrotoxicity" Nature Vol
304:633, 1983

oChronic exposure to mercury may cause an excess of serum proteins in
the urine which may progress to nephrotic syndrome and peculiar
susceptibility to infections that break into and modify the course of
any pre-existing disease.

--Friberg et al, 1953 "Kidney Injury after chronic exposure to inorganic
mercury" Archives of Environmenal Health Vol 15:64, 1967; Kazantis et
al, 1962 "Albuminuria and the Nephrotic Sundrome Following Exposure to
Mercury" Quarterly Journal of Medicine Vol 31: 403-418, 1962; Joselow
and Goldwater, 1967 "Absorption and Excretion of Mercury in Man and
Mercury Content of "normal" Human Tissues" Archives of Environmental
Health Vol 15:64, 1967

oMercury fillings can contribute to a higher level of mercury in the
blood, and can affect the functioning of the heart, change the vascular
response to norepinepherine and potassium chloride, and block the entry
of calcium ions into the cytoplasm.

--Abraham et al, 1984 "The Effect of Dental Amalgam Restorations on Blood
Mercury Levels" Journal of Dental Research Vol 63 No.1:71-73,1984; Kuntz
et al, "Maternal and Cord Blood Background Mercury Levels: A
Longitudinal Surveillance" American Journal of Obstetrics and Gynecology
Vol 143 No. 4: 440-443, 1982; Joselow et al, 1972; Mantyla and Wright,
1976; Trakhtenberg, 1968; Oka et al, 1979

oMercury exposure from amalgams leads to interference with brain
catecholamine reactivity levels, has a pronounced effect on the human
endocrine system, and accumulates in both the thyroid and pituitary
glands, reducing production of important hormones.

--Carmignani, Finelli and Boscolo, 1983; Kosta et al, 1975; Trakhtenberg,

oMercury induces the thyroid gland to absorb an increasing amount of
nuclear radiation from the environment.

--Trakhtenberg, 1974

oMercury can impair the adrenal and testicular steroid hormone
secretions, cause intolerance for stress and decreased sexual ability.
In rats, it causes subnormal fertility and sperm production.

--Burton and Meikle, 1980; Khera, 1973; Stoewsand et al, 1971; Lee and
Dixon, 1975; Thaxton and Parkhurst, 1973

oMercury in the body can produce contact dermititis and reduced function
of the adrenal glands (Addison's disease), producing progressive anemia,
low blood pressure, diarrhea and digestive disturbances.

--Alomar et al, 1983

oMercury has a distinct effect on the human immune system, especially
the white blood cells. Mercury ions have been observed to cause
chromosomal aberrations and alters the cellular genetic code. Mercury
has the ability to induce chromosomal breakage, alter cellular mitosis,
cause a drop in T-cell production and kill white blood cells.

--Vershaeve et al, 1976; Popescu et al, 1979; Skerfving et al, 1970,1974;
Fiskesjo, 1970

oMercury has an effect on the fetal nervous system, even at levels far
below that considered to be toxic in adults. Background levels of
mercury in mothers correlate with incidence of fetal birth defects and
still births.

--Reuhl and Chang, 1979;Clarkson et al, 1981; Marsh et al, 1980; Tejning,
1968; Kuntz, W.D., Pitkin, R.M., Bostrum, A.W., and Hughes M.S., The
American Journal of Obstetrics and Gynecology Vol 143 No.4:440-443,1982

oMercury in the human body can contribute to intelligence disturbances,
speech difficulties, limb deformity, and hyperkinesia (hyperactivity
resulting from brain damage). Abnormally small heads and retardation
were present in 60% of cases.

--Amin-Zaki and Clarkson, et al, 1979