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From the international Amalgam Mailing list : 09 - 02 - 1999 Here are a couple of abstracts of studies at UK directly contradictory to the one ADA is supporting: How can they get directly contradictory results??? Authors: Thompson CM; Markesbery WR; Ehmann WD; Mao YX; Vance DE; Title: Regional brain trace-element studies in Alzheimer's disease. Address: Department of Chemistry, University of Kentucky, Lexington 40506. Journal: Neurotoxicology, 9: 1, 1988 Spring, 1-7 Alzheimer's disease (AD) brain trace-element imbalances in the amygdala, hippocampus and nucleus basalis of Meynert (nbM) are found in most cases to be consistent with those previously reported in samples derived principally from AD cerebral cortex (Ehmann et al., 1986). The elevation of mercury in AD nbM, as compared to age-matched controls, is the largest trace-element imbalance observed to date in AD brain. In addition to the general confirmation of imbalances for Cs, Hg, N, Na, P, and Rb noted previously in cerebral cortex samples, imbalances for Fe, K, Sc, and Zn were observed in two regions and one region also exhibited imbalances for both Co and Se. Persistent imbalances for the univalent cations Na, K, Rb and Cs support arguments for a membrane abnormality in AD. The data presented here also provide the first comprehensive simultaneous multi-element determinations in both control and AD nbM. Wenstrup D; Ehmann WD; Markesbery WR; Trace element imbalances in isolated subcellular fractions of Alzheimer's disease brains. Department of Chemistry, University of Kentucky, Lexington. Brain Res, 533: 1, 1990 Nov 12, 125-31 Concentrations of 13 trace elements (Ag, Br, Co, Cr, Cs, Fe, Hg, K, Na, Rb, Sc, Se, Zn) in isolated subcellular fractions (whole brain, nuclei, mitochondria, microsomes) of temporal lobe from autopsied Alzheimer's disease (AD) patients and normal controls were determined utilizing instrumental neutron activation analysis. Comparison of AD and controls revealed elevated Br (whole brain) and Hg (microsomes) and diminished Rb (whole brain, nuclear and microsomes), Se (microsomes) and Zn (nuclear) in AD. The elevated Br and Hg (Mercury) and diminished Rb are consistent with our previous studies in AD bulk brain specimens. Comparison of element ratios revealed increased Hg/Se, Hg/Zn and Zn/Se mass ratios in AD. Se and Zn play a protective role against Hg toxicity and our data suggest that they are utilized to detoxify Hg in the AD brain. Overall our studies suggest that Hg could be an important toxic element in AD. Whether Hg deposition in AD is a primary or secondary event remains to be determined. -----------------NEW DEVELOPMENT------------------ This is dated Dec 1996 - quite recent. Dr Haleys is a biochemist of world repute - his work is already well known. He is a member of the University of Kentucky's huge multi-million dollar long-term research project examining the causes a Alzheimers Disease - there are probably very few more eminent or knowledgable in this field. Dr Murray Vimy is also a researcher of repute, and a former World Health Organisation consultant. The journal from which the full extract is quoted (FASEB) is a highly regarded and main-stream scientific medical publication. The following quote is from The Valley Advocate, December 5, 1996. "A team of scientists led by Dr. Boyd Haley recently completed a study exposing six laboratory rats to a typical intake of amalgam mercury vapor, diluted to account for the size difference between rats and humans. To the researchers' astonsihment, every rat developed symptoms and brain tissue damage indistinguishable from that of Alzheimer's Disease patients. The reseachers then repeated their experiment only to find the same results. +++++++++ AMALGAM: http://www.listserv.gmd.de/archives/amalgam.html +++++++++ Top |